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Pulsed Magnetic Field Therapy (PEMFT)

Pulsed Magnetic Field Therapy (PEMFT)
and Matrix Repatterning
By Mary Kolosowski, RMT, CMRP


"If you want to find the Secrets of the universe, think in terms of energy, frequency, and vibration."
                                                                   -Nikola Tesla, Physicist & Inventor

The human body produces a subtle electromagnetic field generated by chemical reactions within each and every cell.  The entire planet is permeated by magnetic fields that are generated or affected by the earth's molten iron core, solar storms, weather systems as well as man-made electrical sources.  These external magnetic fields affect the function of the body in both positive and negative ways.
Pulsed electromagnetic therapy (PEMFT), which has been in clinical use for over 40 years, was first successfully utilized in the treatment of non-union (non-healing) fractures.  It has since been applied to many other condition, in order to stimulate cellular repair.  A PEMFT device applies a magnetic field to the body, which induces the production of weak electrical currents in the tissues.  These weak biocurrents can influence the flow of blood and oxygen to the tissues and the flow of ions and nutrients into the cells, which is beneficial in improving cellular bioenergetics.  Research has demonstrated the effectiveness of PEMFT to heal soft tissue wounds, increase range of motion of joints and even suppress inflammatory responses at the cell membrane level to alleviate pain.[1] [2]  In many cases, symptoms can be relieved in as little time as a few minutes, with significantly less side effects than the use of pharmacological agents, which can have toxic effects when used in long term chronic conditions.  Many other advances have recently been made in the application of PEMFT to other diseases, including cancer.

Clinical applications of magnetic field therapy date back over 500 years, but it was not until early 1841 that the potential for the use of electricity to aid in bone healing was reported and further studies continued in the 1950's.  A new treatment for delayed fractures, which used a very specific biphasic low frequency signal to be applied for non-union/delayed fractures was introduced by a team led by Bassett in the 1970's.[3]  In 1974, Alan Dwyer successfully initiated graft incorporation of 11 out of 12 fusion patients by using electrical stimulation in the lumbosacral region, significantly increasing the probability of bone arthrodesis in spinal fusion patients.[4]  The use of PEMFT was approved in 1979 as a safe and effective non invasive medical device designed to stimulate bone growth and post spinal fusion surgeries.[5]

Other applications for PEMFT are post-operative pain and edema, chronic pain, stimulation of stem cell growth and depression in patients who failed to respond to anti-depressants.  Electromagnetic Therapy has been used in treating edema and pain in soft tissue for over 60 years.  PEMFT has shown in clinical trials to be very effective in the treatment of tissue trauma, fundamentally in the early stages of inflammation.[6] [7]  Electrical stimulation in spinal fusion has shown promise in significantly increasing bone arthrodesis. In failed fusion surgeries, PEMF bone growth stimulation has been used successfully to avoid future revision surgery.[8]  The general consensus to the mechanism for healing with PEMF is regarded as that this form of treatment causes a biochemical change at the cellular level to accelerate bone formation.

Another important role for PEMFT is its effects on cartilage homeostasis. By stimulating TGF-beta or the growth factor beta protein that controls proliferation and cellular differentiation.  Healthy cartilage is maintained by anabolic and catabolic activities of articular chrondrocytes.  Cytokines and growth factors regulate synthesis and degradation of the extracellular matrix, like collagen and proteoglycan in chondrocytes and it down-regulates matrix-degrading enzymes.[9] 

Every cell membrane carries an electromagnetic charge, and PEMF's can cause supportive alterations to this by causing movement of ions across the cell membrane. Anti-inflammatory effects have been seen by using low level PEMF's to restore plasma membrane calcium ATPase activity.[10]  Inflammation is therefore decreased since the body's normal cell function, through the exchange of electrons, facilitates movement of regulatory ions across cell membranes.

Cells are the building blocks of all living things.  The body is made up of trillions of living cells that grow, divide and die.  As a young person, cells divide much faster to allow a person to grow.  In adulthood, most cells divide only to replace the dying cells or to repair injuries.  Cancer initiates when cells in a part of the body start to grow out of control.  These abnormal cells continue to grow instead of dying and invade other normal cells and interrupt normal tissue function.  If the DNA (deoxyribonucleic acid) of a normal cell gets damaged, the cell will try to repair itself or go into apoptosis (cell death).  However, if either of these scenarios does not occur, then the cell becomes cancerous and will continue to reproduce abnormal cancerous cells with similarly damaged DNA. 

During the 20th century, there have been incredible advances in cancer research and drug therapies to help eliminate the disease.  Primarily, into understanding of cell dysfunction and the chemistry of the body and as to how drugs alter that chemistry.  Unfortunately, with such therapies there are unfavourable side effects.  However, it cannot be repudiated of the importance of the body's biochemical role is just as significant as its biological properties.  Without the body's electromagnetic fields and electrical currents, this would cause a disintegration of the cells natural function.  Nobel prize winner Dr. Albert Szent Gyorgyi believed that biochemical explanations do not fully vindicate the role of electricity in cellular regulation, that in fact, the cells of the body possess electrical mechanisms and use electricity to regulate and control the transduction of chemical energy and other life processes.  "No doubt, molecular biochemistry has harvested the greatest success and has given a solid foundation of biology. However, there are indications that is has overlooked.  Major problems, if not a whole dimension, for some of the existing questions remain unanswered, if not unmasked." - Szent-Gyorgyi, 1968 Bioelectronics.

In 1970, a book called "Electromagnetic Fields and Life" written by Dr. Aleksandr Samuilovich Presman, pointed out the significance of the correlation of electromagnetic fields and living organisms.  Firstly, that electromagnetic fields have information and communication roles that are employed by living organisms as information conveyors from the environment to the organism, within and among organisms.  And secondly, that electromagnetic fields are involved in life's vital process, by that they facilitate pattern formation, organization and growth control within the organism (Presman 1970).  To answer the question - if living organisms possess the ability to utilize electromagnetic fields and electricity, then it must be considered that physical structures within cells facilitate the sensation, transduction, storage, and transmission of this form of energy.  Communication between cells and within cells allows for regulation and integration of cellular functions and cell growth, however, when a disease like cancer is introduced and causes change in the DNA of normal cells, the cells are no longer regulated by normal control mechanisms. After an injury occurs, the body's healing response will communicate to the body for normal cells to proliferate and will either replace the damaged cells with new cells or scar tissue. 

One significant fact is that, both cancer cells and proliferating cells have a lower cell membrane potential than healthy adult cells.[11] All cells have an imbalance in electrical charges between the inside and the outside of the cell.  This difference is called the membrane potential.  The difference creates a electrochemical force across the cell membrane.  Normal electrical voltage of a human cell is 70 to -110 milivolts.  In a person who is sick, the voltage drops to less than 50 milivolts, and a serious condition, such as cancer, the voltage drops to under 30 milivolts.[12]  While normal cells stop growing after repair is complete, the membrane potential returns to normal, however this is not so with cancerous cells, the electrical potential remains constant at the lower level with cancer cells, causing electrical connections to be disrupted.  A cancer cell’s membrane potential is consistently weaker than a healthy cell.  This also means that the electrical field around the cancer cell membrane is also reduced in strength, causing changes in metabolic functions of the cell. While during cell division and DNA synthesis, the cell membrane falls down to -15 mv, once cell division is completed, the membrane potential returns to normal.[13]  This significance allows the cancer cell to divide more rapidly since the cell membrane potential is constantly set at a weaker potential level.
To summarize, the generalized thought is that a maintained supply of cellular energy and a healthy cell membrane are needed to maintain a normal or healthy concentration of extra and intracellular minerals - sodium and potassium, to support a healthy membrane potential. Normal effects seen when a membrane potential is increased are: enhanced cellular energy, ATP production, increased oxygen uptake, changes in calcium entry, movement of sodium out of the cell, changes in enzyme and biochemical activity, and changes in cellular pH levels.  Whereas, with cancer cells, only five substances can pass in or out of the cell, which are: water, sugar, potassium, cesium and Rubidium (trace mineral needed in metabolic activity).  Note: all cesium compounds should be regarded as toxic because of their chemical similarity to potassium. Because of this similarity, the isotopes 134Cs and 137Cs present in the biosphere in small amounts as a result of radiation leaks, are very toxic. Rats fed cesium in place of potassium in their diet die.  Large amounts cause hyperirritability and spasms, since it prevents oxygen from entering the cell.

With recent studies and decades of research, the use of electromagnetic therapy has increased.  Currently, this therapy is used to normalize the abnormally low trans-membrane potential of cancer cells and injured tissues by modifying the electrical potential of cell membranes.  This changes the electric field of the extracellular membrane, which enhances the current flow through the cell membrane, depending on the frequency applied.  This, in turn, increases the entry of potassium and calcium into the cell, and the movement of sodium and water out of cell, thus reducing intracellular acidity, improving oxygen intake into hypoxic cells and increasing mitochondrial production of ATP through aerobic metabolism.

The use of electromagnetic devices has been applied experimentally in the treatment of cancer, dating back to the 1920's by such researchers as Dr. George Lakhovsky, whose theories on the vibratory nature of cellular activity is well documented.  Lakhovsky hypothesized, that every cell in the body emits electromagnetic radiations similar to those of a radio station and that these radiations act and interact as normal functions of the body. However, when there is illness, there are changes in these radiations. It is then important to return these radiations to their normal frequency state. Lakhovsky understood that there is a dominance between bacterium or disease and the various electromagnetic oscillatory rates of the human cell.  He theorized that the electromagnetic wave structure of the pathogenic bacterium tends to interfere with the normal wave patterns of the infected part of the body, and that the body is capable to overcome infection , then this indicates that the body has the capability to normalize the body's wave mechanism. [14]

In 1931, Lakhovsky invented an instrument called the Multiple Wave Oscillator, that provided a multitude of frequencies that would allow every cell to find and vibrate in resonance in its own frequency. Until his death in 1942, Lakovsky treated and cured a number of cancer patients. While using this technology, others have found the same results. 

In recent years, the science community worldwide has brought on board this technology with positive results on glioblastoma, brain cancer patients. One company in particular in Israel is conducting human tests using an electric field device to kill cancer cells that has no effect on normal cells. Yoram Palti, a Physiologist at the Technion-Israel Institute of Technology in Haifa, who also founded the company Novocure to commercialize the treatment. Testing of this type is also being done in Europe for breast cancer and in the United States.  Most people suffering with cancer, will undergo the regular prescribed concoction of chemotherapy, radiation treatment and surgery to combat the disease, however about 85 to 90 percent of glioblastoma patients' cancer still progresses and their survival rates are still quite low, as explained by Dr. Herbert Englehard, Chief of Neuro-oncology in the department of neurosurgery at the University of Illinois, in Chicago.[15]  The device is worn constantly over certain amount of time. In the glioblastoma patients, the adhesive electrodes are placed over the scalp and weak alternating electric fields pass through the skull into the brain affecting only the cancerous cells. This technique does not introduce foreign substances to the body like chemotherapy or anti cancer drugs, which makes it safer for the patient and allowing the patient to continue normal daily activities with no compromising effects like the illness experienced after chemotherapy.   MRI results months later show a reduction in the tumor size, and full recovery by the end of treatment.  Clinical results in different parts of the world are also showing the same promise with this technology.
Energy Medicine

Energy medicine is a modality that affects positive change in the energetic system of all living things.  Our health is determined by the flow and balance of a person's vital life force energy. Imbalances or blockages in the natural flow of these energy fields in the body cause illness.  The human body has the innate ability to heal itself, however, when it is bombarded with toxins, chemicals and over-prescribed long term drugs.  This is when our bodies have difficulty performing the natural functions it needs to combat illness and disease. "Most over-the-counter and almost all prescribed drug treatments merely mask the symptoms or in some way alter the way the organs or systems such as the circulatory system work. Drugs almost never deal with the reasons why these problems exist, while they frequently create new health problems as side effects of their activities." - John R. Lee, M.D.  The human body is programmed down to the 24,000 genes that present in the human genome.  Biologist, Bruce Lipton, Ph.D. stated, "There are simply not enough genes to account for the complexity of human life or human disease." Research suggests that neurotransmitters, hormones and enzymes can trigger how our genes express themselves in our cells. With relation to energy medicine, these biochemical changes affect the transfer of electromagnetic energy at the cellular level to initiate facilitation. However, when there is a disruption in the natural flow of this intricate system, or as the Chinese call it Qi (chee), this is when disease occurs. There are many ways to reorder this flow system and one of which, is through the energetic process of electromagnetic therapy.

Matrix Repatterning

Matrix Repatterning is a process of assessing, locating and releasing significant tension patterns within the tissues of the body.  This is a revolutionary new advance in the field of energy medicine, was first introduced by internationally renowned developer and educator, Dr. George Roth. This incredible new approach in pathophysiology is based on the scientific principles of the tensegrity structure of the body. Tension patterns are generally created by forceful injuries to the body structure or from scar tissue caused by surgery or injury.  Excessive force to dense tissues such as bone or internal organs may be absorbed by the structure as trapped energy within the cellular matrix.  Due to the network of connective support tissue throughout the body, one area of strain can transmit strain to multiple sites.  These changes to the structure can manifest to repetitive irritation to joints and ligaments, cause chronic muscle tension, and organ disfunction or local tenderness to the body structure surface.  Over a persons' lifetime, there are an accumulation of falls, injuries, surgeries and dental work that the body endures, some of which do not always heal completely.  Eventually these cumulative layers of injuries build to the point where the body's ability to compensate will reach its limit, and can no longer contain balance.  The human body has a safe guard to protect humans from dying, in the form of pain.  This is the brain's way of signaling that there is a problem.  Standard diagnostic testing looks for bone or organ abnormalities, however changes in the fascia or the body's connective tissue is difficult to observe, so it is often overlooked. Doctors often prescribe medications for chronic pain with some temporary relief, however the problem still remains for years until the condition worsens, while also causing other side effects.   Most often in chronic cases, symptoms are the direct result from the compensatory stress created in the body caused by a primary site of restriction. As the brain adapts to pain, the primary lesion is longer symptomatic, however if the lesion does not heal properly, then this forces the body to compensate and cause stress, pain and inflammation in other areas of the body.
Tensegrity Matrix

Tensegrity Matrix Model is a structural model of the body comprised of interconnected cellular and tissial/fascial tensions that holds the body supported in a balance between stability and mobility.  "The word 'tensegrity' is an invention: a contraction of 'tensional integrity'.  Tensegrity describes a structural relationship principle in which structural shape is guaranteed by the finitely closed, comprehensively continuous, tensional behaviors of the system and not by the discontinuous and exclusively local compression member behaviors. Tensegrity provides the ability to yield increasingly without ultimately breaking or coming asunder." -Buckminster Fuller[16]   

Based on the structural model at the cellular level, the biomechanical properties of the body structure allow it to move and respond to certain stress and trauma. The bones are the compression struts, and the muscles, tendons and ligaments are the tension-bearing components that allow a maximum amount of strength by the geodesic positioning of key proteins and molecules, as described by Donald Ingber, M.D., Ph.D.  The cytoskeleton of a living cell is a framework of interconnected microtubules and filaments resembling a geodesic dome constructed of long struts joined by cables.  The struts are connected into triangles, pentagons or hexagons affixed to each other allowing for flexibility and tension.  A description of the hexagonal shapes found on a soccer ball is relative to the tensegrity model that offers maximum amount of strength that is distributed to balance mechanical stress. Cells contain an internal framework or cytoskeleton composed of molecular protein polymers - microfilaments, intermediate filaments and microtubules; but are also connected by an anchoring scaffolding that secure the body called the extracellular matrix.[17]   These components also act as the struts and cables that stabilize the cell shape.

After experimentation with a tensegrity model using dowels and elastic bands to emulate a cell's cytoskeletal shape and connections, Ingber discovered that applying pressure down on the model forces it into a rigid, flattened state.  As soon as the pressure was removed, the energy stored in the tensed filaments caused the model to return to its original spherical shape.  Ingber applied this theory to living cells and was able to successfully show that tensegrity structures mimic the known behaviour of living cells.  The cytoplasm as Ingber describes is surrounded by membranes and penetrated by viscous fluid, a well tuned machine of network of molecular struts and cables that stabilize the cell's shape. If the cell and nucleus are physically connected by tensile filaments and not solely by fluid cytoplasm, then pulling on receptors at the cell surface should produce immediate structural changes deep inside the cell.[18]

 Researchers discovered that the existence of a tensegrity balanced form, provides the ability to integrate mechanics and biochemistry down to the molecular level of the cell.  By this evaluation, the Heidemann team in the 1980's at the Michigan State University, discovered that the mechanical restructuring of the cell and cytoskeleton communicates to the cells and reprograms the cells to adapt to changes in their environment.  Whereby the cells were stressed in their matrix in different conditions causing the cells to enter into division-where cell environment was stretched, or entered into apoptosis (cell division) - due to the competition in a limited space forcing the cell to prevent tumor formation.  But the middle ground between the two extremes allowed for normal tissue function.

At the John Hopkins School of Medicine, Donald S. Coffey and Kenneth J. Pienta made the discovery that tensegrity structures function as coupled harmonic oscillators.[19] Meaning that every cell and its parts down to its DNA, exhibit resonate vibratory frequencies.  Therefore, with forced tension transmitted throughout the tensegrity complex, all the interconnected elements are affected.  This study demonstrated how the extracellular matrix environment communicates and programs the living cell, which is vital to the understanding of new approaches to the body's ability to heal and it is the importance of the mechanical and electronic properties of the extracellular matrix that influences overall health and disease.
Primary Restriction

The intracellular and extracellular matrix is strong as well as very flexible, however when a significant force is applied by an injury, energy is absorbed. This absorption changes the molecule arrangement within the protein fibers causing expansion of the cell forcing it to become rigid and inflexible - creating a primary restriction.  These restrictions transmit tension throughout the body producing symptoms of pain and strain to other areas not local to the initial area of impact.  Over time subsequent injuries, surgeries and other altering tensions cause the body to become less flexible.  As the body becomes more out of balance, the probability of increasing pain and strain is higher with even minor injuries or even simple lifestyle changes like exercise that may cause injury due to the inflexibility of a strain already present.

Several factors affect the matrix such as mechanical: laws of physics state that the more dense a substance is, the more mechanical energy will be absorbed from impact.  As previously discussed, electromagnetic factors affect all molecular structures, like the matrix, each molecule has a specific vibratory frequency for it to function in a normal state.  However, with injury to structure causing rigidity and strain, this changes the arrangement of protein filaments and its molecules - also changing its frequency.  Therefore structure equals its electrical state.  Another factor that directly affect the molecules of the matrix is chemical.  Cells are surrounded by water internally and externally.  Changes to the extracellular and intracellular fluids can be altered by the inefficiency of organs to effectively filter and dispose of toxins or process properly vital body elements to support cellular life, like minerals such as calcium, sodium and potassium.  This leads to structural and electrical changes to the cells and the extracellular matrix, furthermore altering the body's ability to function at a normal balanced health.  Lastly, psychological factors affect body function at the extracellular level since our emotions and thoughts are linked to electrical signals that affect muscles, for example, positive or negative thoughts affect our stress or relaxation levels.

Matrix Repatterning views the body as an interconnected whole...symptoms of low back pain may even originate from a tooth, while the tension resulting in headaches may be coming from a restriction in one of the bones in the lower leg.[20]  By locating primary restrictions and releasing that stored energy, this returning the normal function of the extracellular matrix to an electrical and structural balanced state.  
Energy medicine is a radical innovative approach to understanding the body contrary to the limited conventional thinking of western medicine.  With this new awareness and ongoing research into cellular biology, humanity is closer to unlocking the fascinating mysteries of the human body and the intricate processes that govern health.



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[15] Katherine Bourzac. Electric Fields Kill Tumors. Article. Technology Review  Wednesday August 8, 2007
[16] Synergetics, RB Fuller, Macmillan, New York, 1975
[17] Ingber DE. The Architecture of Life. Scientific American 1998;278:48-57
[18],20 Ingber DE. The Architecture of Life. Scientific American 1998;278:48-57
[20] George Roth, DC, ND  The Matrix Repatterning Program for Pain Relief ©2005